Category: Endocytosis

Supplementary MaterialsRevised Dietary supplement figures 41598_2019_39480_MOESM1_ESM

0 commentsEndocytosis

Supplementary MaterialsRevised Dietary supplement figures 41598_2019_39480_MOESM1_ESM. monomeric -synuclein. NDGA analog-pretreated -synuclein didn’t aggregate also without NDGA-analogs in the aggregation combination. Strikingly, NDGA-pretreated -synuclein suppressed aggregation of na?ve untreated aggregation-competent monomeric -synuclein. Further, cyclized NDGA reduced -synuclein-driven neurodegeneration in model in which expression of human being wildtype -synuclein in dopaminergic neurons prospects to progressive neurodegeneration71. Animals ….  Read More